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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76843 | Tebentafusp | ||
Tebentafusp (IMCgp100) 是靶向 gp100(一种黑色素瘤相关抗原)的双特异性融合蛋白。该药物通过其 T 细胞受体 (TCR) 高亲和力结合域以及抗 CD3 T 细胞接合域,指引 T 细胞针对表达 gp100 的肿瘤细胞进行杀伤。进一步,Tebentafusp 促进炎症细胞因子和细胞溶解酶的释放,直接导致肿瘤细胞裂解。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05455 |
CD3E & CD3G Heterodimer Protein, Cynomolgus, Recombinant (hFc)
CD3e molecule, ε (CD3- |
Cynomolgus | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74.9 kDa and the accession number is Q95LI5.2&NP_001270839.1. | |||
TMPY-02701 |
CD3 epsilon/CD3e Protein, Rhesus, Recombinant (His)
CD3e molecule, ε (CD3- |
Rhesus | HEK293 Cells |
CD3 epsilon/CD3e Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.3 kDa and the accession number is G7NCB9. | |||
TMPY-00616 |
CD3 epsilon/CD3e Protein, Canine, Recombinant (hFc)
CD3e molecule, ε (CD3- |
Canine | HEK293 Cells |
CD3 epsilon/CD3e Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is P27597. | |||
TMPY-03745 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d molecule,... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3- |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-01191 |
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)
IMD18,CD3 epsilon,T3E,CD... |
Human | HEK293 Cells |
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P07766. | |||
TMPY-05374 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His), Biotinylated
T3D,CD3d molecule, δ (CD... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234&P07766. | |||
TMPY-01196 |
CD3D Protein, Human, Recombinant (His)
CD3 δ,CD3 delta,CD |
Human | HEK293 Cells |
CD3D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11 kDa and the accession number is B0YIY4. | |||
TMPY-05457 |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc)
CD3e molecule, epsilon (CD3 |
Human | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 78.4 kDa and the accession number is NP_000724.1&NP_000064.1. | |||
TMPY-04010 |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc-Flag & mFc)
T3E,TCRE,CD3e molecule, ... |
Human | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc-Flag & mFc) is expressed in HEK293 mammalian cells with Fc-Flag, mFc tag. The predicted molecular weight is 76.9 kDa and the accession number is NP_000724.1&NP_000064.1. | |||
TMPY-06108 |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant
CD3d molecule, delta (CD3 |
Mouse | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.4 kDa and the accession number is P04235&P22646. | |||
TMPY-03190 |
CD3D Protein, Human, Recombinant (hFc & FLAG)
CD3-δ,CD3 delta,IMD19,T<... |
Human | HEK293 Cells |
CD3D Protein, Human, Recombinant (hFc & FLAG) is expressed in HEK293 mammalian cells with hFc and Flag tag. The predicted molecular weight is 37.8 kDa and the accession number is B0YIY4. | |||
TMPY-06028 |
CD3E & CD3G Heterodimer Protein, Rhesus, Recombinant (hFc)
CD3e molecule, epsilon (CD3 |
Rhesus | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.4 kDa and the accession number is XP_014971302.1&NP_001253854.1. | |||
TMPY-06499 |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant (Fc-Flag & Fc-His)
CD3d molecule, delta (CD3 |
Rhesus | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 76.63 kDa and the accession number is F6WI60-1. | |||
TMPY-06348 |
CD3D & CD3E Heterodimer Protein, Cynomolgus, Recombinant
CD3d molecule, delta (CD3 |
Cynomolgus | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.63 kDa and the accession number is Q95LI8-1. | |||
TMPY-03328 |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant
CD3d molecule, δ (CD3- |
Rhesus | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.7 kDa and the accession number is G7NCB9. | |||
TMPY-06641 |
CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (hFc)
CD3e molecule, ε (CD3- |
Cynomolgus | HEK293 Cells |
CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.56 kDa and the accession number is Q95LI5-1. | |||
TMPY-03546 |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Flag & His)
CD3d molecule, δ (CD3- |
Mouse | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 29.2 kDa and the accession number is P04235&P22646. | |||
TMPY-03073 |
CD3D Protein, Mouse, Recombinant (hFc)
CD3d molecule, δ (CD3- |
Mouse | HEK293 Cells |
CD3D Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.4 kDa and the accession number is P04235. | |||
TMPY-02747 |
CD3D Protein, Cynomolgus, Recombinant (His)
CD3d molecule, δ (CD3- |
Cynomolgus | HEK293 Cells |
CD3D Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11 kDa and the accession number is Q95LI8. | |||
TMPY-02943 |
CD3D Protein, Cynomolgus, Recombinant (hFc)
CD3d molecule, delta (CD3 |
Cynomolgus | HEK293 Cells |
CD3D Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.6 kDa and the accession number is Q95LI8. | |||
TMPY-04148 |
CD3D Protein, Canine, Recombinant (hFc)
CD3d molecule, δ (CD3- |
Canine | HEK293 Cells |
CD3D Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.2 kDa and the accession number is A0A8C0PNZ1. | |||
TMPY-00628 |
CD3 epsilon/CD3e Protein, Rat, Recombinant (hFc)
CD3e molecule, epsilon (CD3 |
Rat | HEK293 Cells |
CD3 epsilon/CD3e Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.1 kDa and the accession number is A6J423. | |||
TMPY-02690 |
CD3 epsilon/CD3e Protein, Rhesus, Recombinant (hFc)
CD3 ε/CD3e,CD |
Rhesus | HEK293 Cells |
CD3 epsilon/CD3e Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38 kDa and the accession number is G7NCB9. | |||
TMPY-06874 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (His)
CD3d molecule, delta (CD3 |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.75 kDa. | |||
TMPY-02470 |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Fc-Flag & Fc-His)
CD3d molecule, δ (CD3- |
Mouse | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Mouse, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 76 kDa and the accession number is P04235&P22646. | |||
TMPY-05037 |
CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (hFc & His)
CD3epsilon,CD3,CD |
Mouse | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (C-human IgG1-Fc & His & C-human IgG1-Fc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.4 kDa and the accession number is NP_031674.1&NP_033980.1. | |||
TMPY-05124 |
CD3 epsilon/CD3e Protein, Human, Recombinant (His), Biotinylated
CD3e molecule, ε (CD3- |
Human | CHO Cells |
CD3 epsilon/CD3e Protein, Human, Recombinant (His), Biotinylated is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P07766. | |||
TMPY-04697 |
CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (hFc)
CD3e molecule, epsilon (CD3 |
Mouse | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is NP_031674.1&NP_033980.1. | |||
TMPY-05478 |
CD3 epsilon/CD3e Protein, Human, Recombinant (hFc)
CD3 ε/CD3e,CD |
Human | HEK293 Cells |
CD3 epsilon/CD3e Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.5 kDa and the accession number is P07766. | |||
TMPY-04867 |
CD3 epsilon/CD3e Protein, Human, Recombinant (His)
CD3e molecule, epsilon (CD3 |
Human | CHO Cells |
CD3 epsilon/CD3e Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P07766. | |||
TMPY-05243 |
CD3D Protein, Human, Recombinant (hFc & FLAG), Biotinylated
CD3 delta,CD3-δ,CD |
Human | HEK293 Cells |
CD3D Protein, Human, Recombinant (hFc & FLAG), Biotinylated is expressed in HEK293 mammalian cells with hFc and Flag tag. The predicted molecular weight is 37.8 kDa and the accession number is B0YIY4. | |||
TMPY-06878 |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc-Flag & Fc-His)
CD3e molecule, epsilon (CD3 |
Human | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 78.36 kDa and the accession number is NP_000724.1. | |||
TMPJ-01259 |
CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (aa 22-117, hFc)
CD3 epsilon,T-cell antigen receptor co... |
Cynomolgus | HEK293 Cells |
T-cell surface glycoprotein CD3 epsilon chain, also known as CD3E, is a single-pass type I membrane protein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. The CD3 epsilon subunit of the T cell receptor (TCR) complex contains two defined signaling domains, a proline-rich sequence and an immune tyrosine activation m... | |||
TMPJ-00089 |
CD3 epsilon/CD3e Protein, Human, Recombinant (hFc & Avi), Biotinylated
T-Cell Surface Antigen T3/Leu-4 ε Chain,T3... |
Human | HEK293 Cells |
T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors... | |||
TMPK-00697 |
CD6 Protein, Human, Recombinant (His)
CD6,TP120,T12 |
Human | HEK293 Cells |
The cell surface glycoprotein CD6 is expressed on leukocytes and mediates T cell trafficking across endothelial cell barriers. CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse. | |||
TMPH-02275 |
Lck Protein, Human, Recombinant (His)
|
Human | E. coli |
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules... | |||
TMPJ-01186 |
TRIM Protein, Human, Recombinant (His)
pp29/30,TRIM,HSPC062,TCRIM,TRAT1,T-Cell Re... |
Human | E. coli |
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. | |||
TMPJ-00439 |
BTNL6 Protein, Mouse, Recombinant (His)
EG624681,BTNL6,NG13,Butyrophilin-like 6,Gm6519 |
Mouse | HEK293 Cells |
Butyrophilin-like 6 (BTNL6) is a member of the BTN/MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heteromeric protein with BTNL1, and the presence of this complex is correlated with expansion of gamma δ T cells, especially those containing V gamma 7Vδ4 TCR. Btnl6 shows striking sequence similarity to Skint1; is also largely restricted to an epithelial tissue (the small intestine) ... |